Advice You - Business

Declining a job offer is something you might consider during your career.

Sometimes, a job o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ffer doesn’t look as good as you’d hoped, sometimes things change in your situation that make

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

the potential job less desirable, maybe it’s something else.

Here are some common reasons f

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

or turning down a job offer that you’ve received:

Inadequate compensation, benefit

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s, vacation, bonus, stock options, etc.

A disagreement over job title and/or job r

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

esponsibilities

A change of heart either regarding your current employer or the po

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

tential new employer

A gut feeling that “something just isn’t right” with the new

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

employer

You receive another job offer that you prefer to this one.

A c

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

hange in your personal situation that just makes the new job less attractive or impossible to

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

accept. The thing to remember when turning down a job offer is that you will

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ost likely burn your bridges with the particular company you are rejecting.

No hiring manage

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

r likes to have people decline a job offer because it most likely means they have to start th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

eir search again from scratch to fill the position.

Chances are that they have already turne

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

d down other candidates for the job that in hindsight, they wish they’d offered the job to.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Before declining a job offer, make sure you’ve carefully thought through the ramifications of

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

doing so.

If you are unhappily employed, turning down the job offer simply means you are st

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ill stuck in a job you don’t like and will most likely need to address this problem again sho

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

rtly.

If you are unemployed, declining a job offer means that your job search is going to ha

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ve to continue for now.

Either way, declining a job offer is an important decision that shou

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ldn’t be taken lightly especially after you’ve put the effort forth to actually get the offer

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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