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    Nurses perhaps the best friend of a patient. Though they get paid for their job, yet the care and concern they exhibit for the patient is unparalleled
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    and remarkable. The nursing territory generally belongs to females. But even men like women can take up this profession after adequate training. Howe
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ver, since past few years a decline is seen in the number of people taking up nursing as a career. There can be many reasons behind it. So, the primar
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    y task of this article will be to enumerate these various causes along with the consequences of shrinking number of registered nurses day by day.

    Exp
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    loring the different causes:

    Less number of schools can be a foremost factor. There are not many schools that run programs to make future nurses.

    Ad
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ding to the plight is the fact that the schools that exist are in an awful condition. There is not just lack of funds, laboratories and clinical equip
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ments here but the faculty too is not enough and well qualified. These issues preclude many people from entering into this profession. While those who
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    enter the program confront problems at all stages and at times end up giving it up or leaving it in the middle.

    The age factor is another drawback.
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    The average age for the registered nurses is significantly high. So, the moment these registered nurses retire, there occurs an acute shortage of new
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ones.

    No appropriate measures are taken to train new nurses. Even the hospitals that take up this task are reluctant to spend good amount on training
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    nurses. The medical and other facilities are very poor. This entails reluctance on the part of individuals to seek employment as a nurse.

    Novel and
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    advanced courses- many new and advanced courses like MBA, Mass Communication and so forth are picking pace these days. They are usually equipped with
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    best facilities and funds and are seen fetching rich jobs. So more guys and gals are willing to make a wealthy career via such courses.

    The restricte
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    d scope for growth, relatively low salary structure and tremendous workload are also the debarring features. The job of a nurse is deemed to be quite
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    a stressful job nowadays, that requires prolonged working even at odd hours.

    The Outcomes:

    A surge in demographic levels has resulted in more number
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    of big and small diseases and so large number of patients. But the shortage of nurses adversely affects patients in hospitals. They fail to get adequ
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ate care and vigilance. Studies have revealed that in past few years, greater numbers of patients are dying in hospitals due to negligence. The ailing
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    men and women do not take medicines on time and there are no nurses to keep an eye on them all round the clock and instigate them to take their doses
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    regularly. Thus, the health care has received a major setback due to the diminishing number of registered nurses these days.

    The dip in nursing care
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    er has given birth to temporary and contract nursing. This type of nursing has proved to be a little help in meeting the scarcity of registered nurses


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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