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    Business phone systems can be purchased from telephone service providers, other manufacturers through their sale
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    s networks or through Internet. Most businesses usually need to have several telephones to run their operations
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    nd it is neither practical nor necessary to have each telephone connected to the external (service provider's) n
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    etwork. Communication systems containing internally operated switching systems are available that do not require
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    connecting each telephone set to the public telephone network.

    Most businesses usually install an internal phon
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    switching system (called "Private Automatic Branch Exchange" or PABX) that provides an interface between intern
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    al telephone instrument's network at one end and external telephone services provider at the other. Latest elect
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    onically controlled PABX systems are called EPABX systems.

    PABX equipment needs to be purchased by business own
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    rs along with required number of instruments. Arrangements need to be made to install all equipment at their pre
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    mises. In addition, some extra outside lines are useful for making and receiving calls to the public telephone n
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    twork. Businesses with multiple branches can connect their PABXs together with trunk lines.

    Similar services ca
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    also be provided by installation of equipment off site at a central provider and delivering services over the p
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ublic telephone network. This modification is called a hosted PABX. Many local phone companies offer a service i
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    which each extension has a trunk line connected to the telephone company's Central exchange. In addition to tel
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    phone sets, extensions such as fax machines, computer modems and many other communication devices can be connect
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    ed to a PABX.

    Modern day business telephone systems are highly complex and expensive. It is therefore better to
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    consult a technical expert to help choose an appropriate system, before making a deal. Some issues that need car
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ful consideration are compatibility with existing equipment and internal network as also compatibility with the
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    service provider's equipment and network. Flexibility for future expansion, ease and availability of professiona
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    maintenance and additional or spare components from original equipment supplier are some other important issues


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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