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Kids love these glow-in-the-dark sticks. Especially after dark. They can

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

wave them in the air, connect them together to make bracelets or necklace

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s. Kids cannot resist them

They are little tubes filled with a flouresce

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nt gel. When the sticks are bent, the internal lining is broken activatin

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the flourescent light. They glow for about 6 hours and come in 5 or 6 di

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

fferent colors. Most packages also come with connectors so that the kids

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

can create bracelets and necklaces with the glow sticks.

Glow sticks are

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

a great little money maker. You can sell them for fundraisers or to put s

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ome money in your pocket. You never see this in stores, at least here in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Dallas. Buying 500 8″ glow sticks will cost around $30 to $40 with

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

shipping giving you a unit price of 8 cents each.

During the summer, we

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

sell them at our swim meets around dusk at 3 for a dollar. Our concession

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

manager walks out of the concession stand at sunset wearing these stick

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

on her hair and as a necklace. Before you know it we have kids lined up a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

the concession stand waiting to buy their own glow sticks. We have sold

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

them for a dollar each in the past. A friend of mine was selling them for

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

$3 at a local Oktoberfest. To see some current buys on glow sticks check

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

out eBay.

There are lots of ways to sell them. At festivals, sporting ev

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ents, and raves. Just about anyplace where people, especially kids, congr

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

egate after dark.

Besides they are a lot of fun to have around the house

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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