Advice You - Business

Ramie is commonly known as China grass from which the ramie fibre is derived. The ramie plan

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t is a hardy perennial, which can be harvested up to 6 times a year. It produces a large num

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ber of un-branched stems from underground rhizomes and has a crop life from 6 to 20 years. T

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

he fibres need chemical treatment to remove the gums and pectin found in the bark. The proce

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ss of transforming the ramie fibres into fabric is similar to the process used for manufactu

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ring linen from flax.

The true ramie or 'China Grass' is also known as 'white ramie' and is

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

the Chinese cultivated plant. It has large heart shaped, crenate leaves covered on the unde

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rside with white hairs that give it a silvery appearance. The fibre is very fine like silk,

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

and being naturally white in color does not need bleaching. Long before cotton was introduce

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

d in the Far East, it was used for Chinese burial shrouds over 2,000 years ago. It was used

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

in mummy cloths in Egypt during the period 5000 - 3000 BC. Ramie's popularity increased in t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

he mid 1980s with a fashion emphasis on natural fibres.

Chemically ramie is classified as a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

cellulose fibre, just as cotton, linen, and rayon. The leading global producers of ramie ar

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e China, Taiwan, Korea, the Philippines and Brazil. Ramie is often blended with cotton to ma

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ke woven and knit fabrics that resemble fine linen to coarse canvas. Ramie is commonly used

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

in clothing, tablecloths, napkins and handkerchiefs. It is often blended with cotton in knit

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

sweaters. Outside the clothing industry, ramie is used in fish nets, canvas, upholstery fab

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

rics, straw hats and fire hoses. The main producers of ramie today are China, Brazil, Philip

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

pines, India, South Korea and Thailand. Only a small percentage of the ramie produced is ava

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ilable on the international market. Japan, Germany, France and the UK are the main importers

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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