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  • Advice You - Team Building Lessons from the Modern Cave Man - Part 1

    In the beginning…

    The caveman needed to survive. Man found safety in groups. It was not a matter of preference, it was a matter of necessity. If you were not a part of a group, your chances for survival were slim. Conformity to the majority became necessary to stay in a group and p
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    hysical strength was the dominant factor for group leadership. Those who were strong and successful in the art of survival had the majority influence toward that conformity and only the strong challenged these leaders. If you challenged the leadership, you needed to be prepared to f
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ight. And, if you lost, you were forced to leave the safety of the group and fend for yourself. The risk was great so there were few challengers and it became an ingrained survival response to gain acceptance from the group, so people just kept quiet.

    It was a time of compliance!

    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    …Then came the significance revolution

    The caveman's brains got bigger and more developed. Individuals became torn between finding there own path and gaining there own recognition, verses conforming to the group. Physical strength was no longer the dominant factor for influence. No
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    w, people could think! Survival was no longer the acquisition of food and shelter; it had become a fight of ability. The more intelligent you were (and able to apply it), the more valuable you had become. The more influence you could exert over others, the more powerful you became.
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    We began to compete for significance trying to show others how important and able we are, and if they believed us, or in some cases feared us, we became even more important.

    We created a civilization that needed to be right!

    Then came the industrial revolution…

    …and groups evolve
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    d into teams but the fundamentals of our survival instinct, our emotional evolution and the emotions that drive us were still there, and a major part of our psychology. Our ability to work at our peak in teams depended on the way these emotional drivers and understanding the dynamic
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    they promote.

    Today, the caveman has evolved and the awareness of our psychology has expanded.

    We now seek better ways to improve our selves and our performance, but our caveman nature sometimes gets in the way. While our modern brain is influenced by numerous factors of emotiona
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    l drive, the three that came from our caveman days are still central to our performance in teams:

    The drive to belong The drive for security The drive to be significant

    As with our caveman ancestors, our fear of loss is more important that our potential for gain. Loosing (or the p
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    otential of loosing) our sense of belonging or our sense of security or significance are materialize in caveman like reactions. These reactions are sometimes subtle.

    Our caveman reaction for conformity is driven by our need belong and feel secure in the group, so we keep quiet and
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    comply. And if we do challenge, we are probably depriving others of their significance or security, causing them to react to "protect" themselves. This can either escalate to greater conflict, or it may revert back to compliance and conformity to prevent conflict. Either way, these
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    are still caveman reactions and are NOT useful to high performance teams.

    The greatest obstacle to high performance is the caveman's reactions to loosing significance, in order for the caveman to be right, he must make someone else wrong, and that means, more caveman reactions from
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    the other team members! And the worst part is that reality is not what matters, the caveman reacts on emotion without fact, and so "perception" influences reaction. When someone feels wrong, they feel less able; they may feel like they have less control and therefore are less secur
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    e, they react with aggression or submission out of dissatisfaction, and a lesser desire to cooperate affects their performance and the entire team.

    So how do we get the caveman out of our teams so we can stop reacting and act like the evolved humans we have become, able to perform
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    t the peak of our abilities?

    There are 4 stages to our evolution into "awakened" team members

    Each stage is a stage of awareness. It awakens our greater perception. But for it to be effective, the entire team has to take this journey. But there are consequences, once team members
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    have awakened, they will never view teams again in the same way. They can never go back to the way it was and can never be satisfied with mediocrity. Each stage opens our eyes to the caveman within ourselves and others, and it lets us use the intelligent part of our brain to send th
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    is caveman back when he tries to invade our minds and body. Different team members may be at different stages in their evolution, where are you? These 4 stages are as follows:

    Stage 1: Acknowledge the primitive caveman in you

    Look at the behavior you have had in the past. How ma
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ny times have you gone against your better judgment to "go with the flow"? Discover your need to belong to the group, to be accepted by your pears. How has this need manifested itself in your interaction with others? What has it prevented from achieving? Would your relationships Rea
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    lly be damaged if you expressed your views and opinions or confronted someone else's potentially bad decision, or is it possible you would gain more respect. As a leader, is it more important for you to be liked than to get the expected results?

    By reflecting on the behaviors you h
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ave displayed in the past, and realizing the damage you are doing to your personal effectiveness and the effectiveness of those around you, you can see the primitive caveman for what he is. This is the first step in your evolution.

    For the Second and Third stages, Please read Part


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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