Advice You - Business

Binding machines are used for fastening loose pages, plastic covers, or fabric layers togethe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

r using plastic or metal wires. Binding machine lubrication must be done frequently, even if

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

he operator's manual does not indicate the need to lubricate every point.

Binding machine lu

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

brication must be applied to all parts of the machine that are in motion. Each point must be

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ubricated with a small drop of oil. Binding machine lubrication should be applied after every

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

four or five hours of machine use.

Before oiling, take off the cover and rotate the hand-whe

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

el in the normal rotating direction to locate all movable contact points on the machine. Cont

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nue to keep the machine rotating while oiling it, in order to ensure that all parts are well

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ubricated. Special attention is to be given to parts such as the hook race and the correspond

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ing bobbin case as well as the needle bar because they are the main wear areas. If oil contam

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nation is not a big problem for your job, oil the hook race at each change of the bobbin. The

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

oiling of the hook race is difficult in bobbins that are inserted under the bed and is easy i

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

f the bobbin is loaded from the top of the bed.

Binding machine lubrication can be done usin

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

manual oiling systems or automatic oiling systems. Manual oiling systems require an operator

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

on a regular basis. Automatic oiling systems can lubricate all parts at regular intervals. Th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e oil in automatic systems can be distributed evenly using a pump. In automatic oiling system

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

, oil is filled in a reservoir. Larger oil reservoirs have calibrated oil indicator levels. M

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ny binding machine lubrication systems have sight windows or bubbles showing the pressure of

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

the oil in the system. Advanced pressure systems have adjustment needles or valves to control

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

the flow of oil to critical points. All automatic oiling systems have an oil return mechanism

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.adviceyou.org.ua/article/20290/adviceyou-Binding-Machine-Lubrication.html">Binding Machine Lubrication</a>

BB link (for phorums):
[url=http://www.adviceyou.org.ua/article/20290/adviceyou-Binding-Machine-Lubrication.html]Binding Machine Lubrication[/url]

About 98% of the retailers who I talk to complain that their advertising doesn't pay. There are reasons. Here's one.

Partnering is a business relationship that requires planning. Think of some potential partners and services that might benefit your company and put them on your prospect list for partnering.

Tags

Links

Advice You - Binding Machine Lubrication

Related Articles: