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The marking of glass for industrial use has been done for hundreds of years. In the past the methods used have included ink stamp marking, sand blasting, air grit, acid etching, scribing etc.

Industrial

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

applications of glass marking include:

1. Marking of safety information on safety glass used in commercial and residential construction. This includes glass areas around doors and/or entrance and exit lo

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

cations.

2. Marking of glass for commercial and residential construction to identify the glass or door manufacturer [for product identification and marketing/sales activity]

3. Marking of headlamp or tai

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

l light lens in automotive applications for manufactures name, year of manufacture and/or part number. Also used in the manufacture of televisions for marking mirrors and lens.

4. Marking of serial number

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

, product identification, or other manufacturing information for the prevention of theft and validation of warranty claims

5. Marking serial numbers, part numbers, text, or bar codes allowing for parts to

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

be tracked though the production process until final assembly and shipment

The traditional methods of glass marking all involve contact with the surface of the glass product which exposes the product to

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

stress and potential damage. Co2 lasers offer significant advantages for marking glass products. The RF excited sealed beam Co2 laser coupled with a galvo head and software offers the fastest, cleanest,

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

most reliable method for marking and etching glass.

A Co2 laser can laser mark glass with bar codes, especially 2-D or data matrix bar codes, which can easily be coupled with vision systems for reading th

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e data contained in the bar code. The use of bar codes on glass allows for the product to be tracked all the way through the production process until final assembly. This helps assure a continuous uninter

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

rupted supply of product. The laser marked or laser etched bar code can also be used after the sale of the product for identification purposes and validation. This helps to eliminate warranty costs relat

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ed to counterfeit or unauthorized products.

A Co2 laser marked or laser etched bar code can also be read by vision systems in the manufacturing process to determine the identity of the part. Examples inc

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

lude prescription strength of eye glass lens, or the type of front headlamp lens used in a Honda Civic. This ensures that the part is sorted and used properly throughout the manufacturing process and that

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

the correct number of parts is produced based on anticipated sales for final assembled components.

The advances of Co2 laser marking of glass over traditional methods are extensive. These include:

• No

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

contact with the part as in scribing methods thereby reducing the possibility of breakage to and damage of the part, as well as elimination of the maintenance required for the scribe unit

• No solvents,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

thinning, or cleaning agents to purchase and keep in stock as in the case of ink marking or ink printing systems, thereby significantly reducing costs of operation and eliminating the need for continuous m

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

aintenance associated with these various ink printing technologies

• No pads for ink printing to maintain as they can fall to an angle or become turned sideways causing the printed image on the glass to a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ppear sideways or not square

• No need to stop the glass in place and make sure a secure fit with the rubber mask is formed as in the case of Airgrit marking

• With Co2 laser marking for industrial glass

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

applications the product can be marked on the fly [while moving]. If stopped or 'squared' for marking, five to eight lines of text plus logo's can be laser etched in less than 0.5 of a second

• With Co

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

2 laser marking no supplies are necessary and no secondary process exists for cleaning or maintenance

• With Co2 laser marking changes to the mark [different text, different logo, difference shape, etc] c

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

an be accomplished with a simple click and drag command of the mouse

Co2 laser marking for glass in industrial applications is the fastest, most effective, least costly method in which to mark the product

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Right now, you may be so busy creating a method on paper to make your customers like you that you are missing the opportunity to make it happen. Stop worrying so much about finding new customers, overcoming price objections and explaining the advantages you have over the competition. Spend less time in your office meetings and more time with your customers.

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