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    But besides the web hosting services there is a domain market where the battle is even more cruel. The Wall Street Journal today published an article about domain disput
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    e over .NU domain extension.

    .NU indicates "Niue", a tiny South Pacific island near Tonga. Dot-nu is the national internet suffix of this country but it has become very
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    popular in Sweden because ".nu" means "now" in swedish.

    A internet entrepreneur Bill Semich, from Massachusetts got .Nu licence in the late 90's and started exploring i
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    . He thought .nu would be a cheaper alternative to expensive at this time dot-com domains. The american market has not took in the idea of dot-nu domains, however good n
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ews came from Sweden where about 110,000 domains has been sold from Mr. Semich's company called "NU Domain Ltd.".

    Once the domain name business of the american business
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    an has become profitable the Niue island authorities has opened dispute against the ownership over the domain name. Getting money from exploring exploiting the NU domain
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    is important for the island and its 1200 inhabitants. The local government says that it can raise money from dot-nu selling.

    Whos's Right and Whos' Wrong

    The big quest
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    ions is should the governments have to receive the right to control their country's top level domain (TLD) or it is better a private companies to maintain domain under c
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    rtain regulations?

    Mr. Semich who invested more that $100.000 in its dot-nu business has brought the internet to Niue. He made the people from the small island the worl
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    's first nation with free internet access to all citizens by building an wireless network in Niue. He say his company pays voluntary a part of its profit to the local go
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ernment.

    The expression of his interest was at first welcomed by the Niue's authorities. Now the managing director of the local Telecom says that taking control over th
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    e domain name is "a huge issue of national development for us" and insist the Niue must take the ownership over dot-nu from the businessman.

    This is typical bureaucrati
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    reaction you can see worldwide. Governments did not pay attention on internet and online communications in the 80's and in the beginning of 90' and even put obstacles t
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    new internet companies. There are still countries like Cuba, where the possession of computer and the use of internet connection is prohibited.

    Now governments realize
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    the importance and the power of the internet and most of them are trying to control it. The niue government claimed in 2003 that Mr. Semich company must be licenced and
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    the telecom minister shut down the internet service that hos company provided to the citizens. The minister Toke Talagi even sent request to ICCAN to transfer the owners
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ip and management of the dot-nu to the island's government.

    The things would went wrong for the US entrepreneur but local people began to miss the internet service. So
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    restoring the internet service has become a big political issue and a part of the election campaign in Niue in late 2003. A few days before election day, the interim pri
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    e minister allowed the "NU Domain Ltd." to reopen the islands wireless network.

    People got their free wi-fi. Now the authorities are negotiating with the american busin
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ssman to increase the benefits the Niue receives from the domain name.

    The story is available on WSJ's web site. The article's name is "Catchy Web Name Sparks a Battle"


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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