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  • Advice You - The Economics Of E-Book Publishing

    The economics of publishing books in electronic form are too good to ignore.

    When you consider the cost of marketing, publishing, shipping, and returns of printed materials vs. the cost of marketing and shipping an e-book the two are just not in the same
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    league.

    The cost of having a book printed and published exceeds $20,000 for about 3,000 copies. Again the cost of an e-book is $0.

    How to sell and deliver your books to the reader?

    To get your printed book sold you will need to market the book-to-book stores. To ge
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    in the bookstore you need a favorable review of your book. The review process works like this:

    The author sends out press releases to book reviewers representing the genre of the book. If the reviewer becomes interested in the press release, the author will receive a
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    request for a "review copy."

    The author digs into the stash of books, pulls out a copy, attaches a reviewer or a media kit, and pays for the postage. On a $5 book that may add another $5 in shipping materials as well as postage. Many reviewers will ask you to ship you
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    r books by overnight express. The author may find himself spending up to $18 - $25 per reviewer!

    Experts in the self-publishing field, state that you must send between 300-500 review copies to target genre reviewers before your book has a chance to become a hit. If yo
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    send out 500 book copies at a minimum of $10 per book, you have spent another $5,000 of your money.

    Now you have to market the book. It's your job as the self-published author to get the books into the store, and it is your job to move the books from the store to you
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    customers.

    Many self-publishing marketing experts feel it takes around $30,000 per title to effectively market a book.

    So here is the rundown of what it costs.

    What it costs to print and sell a self-published book

    $20,000.00 to print and place a cover on your book
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    .

    $ 5,000.00 to send books to reviewers

    $30,000.00 to market each book effectively.

    $55,000.00 is your total investment.

    Out of your initial 3,000 run of books you have already given away 500 leaving you with 2,500 copies to sell.

    Assuming your retail price is $20
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    per book and you can maintain that retail price for one year, the most you will bring in if you sell every remaining book is: $50,000

    If you subtract the $50,000 you incurred as expenses you will have a net income of only $0.

    Believe me when I tell you that will be t
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    e hardest you have ever worked for free.

    Are these figures realistic? Yes, they are! Ask any self-published author what it cost to print and sell books.

    Now let us use an example of creating or publishing an e-book and bringing it to market.

    We will assume that you
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ill want your own web site. It is possible to sell e-books without one, but lets look at all of the possibilities.

    Let's assume that you have a computer and word processing software. You will need that anyway to self-publish your book the traditional way.

    What it cos
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    ts to publish and sell an e-book?

    1. Cost of a Web site with secure credit card ordering is $50 per year. A good hosting company RD-Webhosting
    2. Cost of an Internet provider is $240 per year.
    3. <
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    i>Adobe Acrobat Software is $269 (One time charge)
  • Create as many e-books as you want with this setup.
  • Marketing costs. You can get by using "sweat equity" in other words you don't need to spend anything. (You just saved $30,000 Congratulations!) I wi
  • cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    l explain marketing later on.
  • Cover Graphics. You don't really need any unless you are posting to Amazon.com or barnesandnoble.com. There are people who will charge $100 or less to create an attractive e-book cover for you. Let's estimate on the high side of $2
  • tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    00. You can use software like Paint Shop Pro or other graphic design software or take a picture, scan it into your computer and use that as your cover art.
  • Review Copies. There are e-book reviewers. You send the reviewers e-mail attachments that include copies
  • t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    of your e-book. Your cost to send it is $0. Think of how many reviewers you can service on the Internet. You will be happy to send out a review copies when you are not paying $10 or $20 per reviewer.
  • Once you own your e-book publishing software, the cost to "pr
  • ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    nt" the e-book in digital form as an Adobe Acrobat, ASCII text, or as a Microsoft Word Document is $0.
  • Your total cost of the e-book production run of 3,000 e-books and your cost of sending these to 500 e-book reviewers including the total marketing costs for
  • y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    one year is $784. Now that you own the software for your next e-book projects, the total cost for each successive e-book is $200.If you sell that $20 book for only $10 as an e-book thus giving your reader 50% savings, you will bring in $30,000.

    Many on-line e-boo
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    sellers are selling e-books at only a 20% discount compared to the printed and bound versions. If you follow that model you will receive $48,000 with out of pocket expense of only $784.

    I am assuming a print run of 3,000 e-books in this example. An e-book is a digita
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    file. If you have orders for 10,000,000 copies for the year, the cost will still remain at $784 for the first year!

    Do you see why this may be the best time in your life to consider finishing that novel or to begin selling e-books and booklets on-line?



    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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