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Everyone creating an eBook would stumble upon the choice on whether to publish your eBook as a PDF or EXE. The differences between the two can be more than ju

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

st the file extensions. Each has its own advantages and disadvantages. So when should you select a specific format?

When you make a search for eBook creation

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

software, you would generally find EXE eBook creation software on the top. Why is this so? Why not PDF? PDF has been on the market for a long time. But eBook

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

creation was not just one thing it is used for. PDF is used by the Goverment and for many important document and manuscripts. PDF's features made many writer

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s publish in that format.

EXE eBooks can be created using many eBook Creation software. These are available in various ranges, from $19 to $200. Many of them

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

come with a brander, which enables your readers to brand your ebook to their name. The interface provided by the EXE eBooks look sleek. People find it easier

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to design web-page like eBook design and interactivity in HTML rather than a Word Processor.

There is a great misconception in the market that PDFs are very

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

costly to create. We hear of the fact that Adobe's PDF creation tools are very costly, and hence is PDF creation. But we shouldn't ignore all the other alter

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

natives available. Today, PDF creation products which provide similar features, are available for free. Most of the Word Processors have PDF exporting feature

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s incorporated in them.

Another misconception is that eBooks published in EXE format look more professional than PDF eBooks. This is certainly wrong. Nowaday

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

, its the content that matters the most. PDFs looks and feels like real paper. A document can be made a lot more professional in a Word Processor using the va

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

rious formatting tools available.

There was one problem with PDF though. It could not be as easily branded as EXE eBooks, which already came with a brander.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

But many solutions for rebranding PDFs have emerged in the market.

EXE eBooks can look difference in different computers, especially if people use various re

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

solutions. This can be evident by seeing many Websites that look difference when seen in difference resolutions. PDFs look the same in all the computers, and

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

one can easily print them.

My personal suggestion would be to go with PDF eBooks. They too have various security options. A quick Google search can lead you

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

to many free PDF creation tools. PDFs can be read in Mac or in any Operating System where Adobe Reader or equivalent is installed. This also includes Operatin

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

g Systems like Linux.

There is a possibility of EXE files getting corrupted or infected with virus. If a person having his PC infected by a virus downloads y

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

our eBook and passes it to his friends, there is a great chance that he is passing away an infected eBook. EXE eBooks carry an overhead. The "reader"

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

; part of an EXE eBook is around 200 to 300 Kb. Your content is compressed and added to it, which results in eBooks more than 300kb.

But if you don't want to

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

speed huge amount of money on PDF branders and want to start a Viral Marketing campaign, i would certainly go with an EXE eBook compiler. The choice is yours

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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