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Electronic mail commonly known as e-mail has permeated most of the fields nowadays providing a way for communication for people from

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

every corner of the world. Through the passage of time, electronic mailing has extended its significance to the business world. And

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

today email is one of the fastest growing means of communication for business to business transactions and business to customer as w

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ll.

Online marketers maximize all the resources at hand to optimize their mailings – from the appearance of the email to its conten

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

t, and many more. Unfortunately emails can get block regardless of the effort done in sending it. Basically there are two common rea

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ons why legitimate emails (e.g. opted in promotional, newsletters) get block. During peak hours (time when most emails are sent), IS

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

’s get overwhelmed and thus experience a temporary technical problem which disables them from sending emails. False positive is anot

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

her reason why emails are not delivered to prospects’ inbox. False positive occurs when a legitimate email is flagged as spam and th

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s redirected to bulk folder instead of having it to the inbox.

In a content based filter, the software looks on the subject line, h

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ader, and content of the message which appear suspicious. The filtering process is very dependent to phrases and words chosen by the

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

user as spam, this means that spam messages with words or phrases not included in the list of the user will make it to the inbox tim

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e and again unless the user creates another filter to deal with those words and phrases. The good side of this filter is, it can be

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ashioned in anyway the user wishes to.

Content Filter is just one type of filter. There are also Bayesian filter, volume-based filt

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r, and etc. In addition, major ISP’s use blacklists (lists of IP addresses of known spammers). Blacklists are not 100 percent accura

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

te, because some the IP addresses included on it don’t send spam.

Blocked legitimate emails are difficult to track. Once an email i

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

sent, online marketers have no means of knowing if the email was sent to the recipients, not unless bounced emails are generated. A

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d since content filters just redirect email to bulk folders, no bounced message is sent to the marketer indicating that the message

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

did not reach the inbox.

I believe it’s time to make every email count. If you think your emails do not reach your prospects inbox,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

in that you get few responses from your emails, you better procure an email delivery assurance system. The said system can help you

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

rack which ISP’s and filters are blocking your emails and help you fix the problems that keep your emails from your prospects’ inbox

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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