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As you know; the bigger your subscriber list, the bigger your paycheck. Imagine now, that your list of 10 in January turned int

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

o 100 in February, and 1,000 in March. What would this do to your paycheck? How nice would June be?

The great thing about the

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

techniques you are going to learn is that once the system starts it automatically continues until you hit a million. How is th

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s possible? The concept is simple and it is all based on a mathematical equation.

The Pyramid Concept:

I kn

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ow, you all shirk at the thought of a “pyramid scheme”. Well, everybody that is except for the hundreds of thousands of people

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

who became rich from them.

Anyway, pyramid schemes are illegal and for good reason. The concept you are about to learn is not

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

a “scheme” just a mathematical formula. And it in no way involves getting or asking money from anyone.

Here’s the Conc

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

pt:

1st month: you find 10 people to sign up for your newsletter. (That’s Easy)

2nd month: get the 10 people who sig

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ned up for your newsletter to get 10 people to sign up (Not as easy, but, you could also replace some of the people by getting

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

0 more people in your 2nd month)

3rd month: Ask the 100 – 200 to find 10 people to sign up for your newsletter

etc….

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

>Why This Concept Won’t Work:

This concept in the way I described above, although it sounds nice, is not practical.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

You will never be able to have your subscribers sign up 10 people for you.

So, then, how is this concept going to be enacted?

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Create a contest or free promotion:

Unfortunately, I can only make this article so long before you get bored,

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

so, I’ll give you the short version.

Here are the steps: (only 1 of the million ideas)

1. Start a “lottery” site or contest

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ite where you give away a cash prize to the monthly winner

2. Tell the contestants that they will get one entry per every 5 pe

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ople they get to sign up for the lottery.

3. All entrants will have a pre-checked opt-in for the newsletter. The only way the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

can win the prize is if they are signed up for the newsletter.

You can see how your subscribers will continually want to get

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

more subscribers so they can get more tickets. It’s a win/win situation.

Summing it all Up

To some, this id

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

a might seem crazy, trite, unoriginal, or even brilliant. I didn’t write this article for you to follow it step by step, but t

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

o get the creative juices in your brain flowing. Sometimes ideas like this will get you thinking along the right creative path

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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