Advice You - Internet and Businesses Online

If you're like most people starting out on the Internet,you've been along this well-worn path:

You try free classified ad sites and get bombarded with spam by people trying to sell you stuff.

You try banner exchange programs and get a handful of click-throughs.

You finally get into the top

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

twenty results in the Search Engines, and then a week later your site has dropped back to number 150.

The Internet may the largest market in human history, but how on earth do you reach those millions of people?

Well, the answer is ezine advertising.

Its the surest way on the Web of reac

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ing your target audience.

Ezines (short for 'electronic magazines') are email newsletters that are sent out regularly to subscribers, like the one you're reading. They're sometimes called 'opt-in' lists because everyone who receives an ezine has chosen to do so.

And that's why ezine adver

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

tising gets results. People read ezines and they'll read your ad. And if you've matched the ezine to the product you're selling, you've reached your target audience.

Have a look at the ads in your favorite ezine - why are they there? Because they get results.

There are currently around 90,

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

00 ezines being published every month. So whatever you're selling, there's more than likely an ezine that will take your ad straight to the audience you want to reach.

Ezine advertising is not only effective, its cheap as well. A 5-line ad in an ezine that goes to 3000 people will cost you

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

between $5 and $20 per issue.

As a general rule, you'll always get back at least the cost of the ad, and usually much more. So there's very little risk.

But there are some tips for successful ezine advertising. Here they are:

1. The first and most important rule in ezine advertising is:

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Track your Ads!". You might place your ad in 5 different ezines and get a hundred responses, but if you don't track your ads, you won't know which ezines were pulling responses and which weren't.

To advertise effectively in ezines, you must learn from experience - its a process of trial an

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d error. Eventually, you'll end up with a handful of ezines that you know are bringing you a high response rate. After that, just keep placing your ads in those ezines and you'll have a guaranteed stream of customers.

But how do you track your ads?

The simplest method is to place a key or

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

code at the end of your email address. If your ad was in this ezine (for example), this is the email address you'd place with the ad:

yourname@yourdomain.com?subject=freezine

Then, when you get a reply with 'freezine' in the subject field, you'll know which ezine it came from.

For a URL,

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

it's the same principle:

http://www.yourdomain.com?freezine

However, if you're going to code your URLs, you'll need a sophisticated webstats program to track the coded URLs. Here are a couple of free ones:

http://www.hitbox.com. http://www.openwebscope.com.

Here's another way to code you

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

URLs : for every ezine ad, create a duplicate of your homepage and name the page after the ezine that your ad will appear in. So, if the ad is appearing in Ezine A, this is the URL you'd place in that ad:

http://www.yourdomain.com/EzineA

Again, you'll need to use a good web stats program

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

o track the hits to your coded URLs.

2. The second rule is to target your audience. It may seem obvious but some advertisers overlook this. If you're selling a web-marketing course, don't advertise in an ezine that deals with stock options; they probably won't be interested.

Use the 'subj

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ect categories' in any ezine directory to find ezines that relate to the product you're selling. You can find a list of 60 ezine directories in 'The Free Directory of Ezines' at:

http://www.netmastersolutions.com/more-directories.html

3. Once you've chosen a number of ezines that target yo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r audience, subscribe to them and examine the ads closely. If you see an ad that keeps repeating issue after issue, you can be pretty sure that its getting results. You've found a good ezine to advertise in.

4. Check to see how many ads are in the ezine. You don't want your ad lost in an ez

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ine farm at the bottom of the newsletter. You probably won't get much response from an ad in an ezine that has 15 or 20 ads per issue. Readers of those ezines have become hardened to the ads and have learnt to skip them.

5. Check to see if the ezine publisher has a policy of never running

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ds for two similar products in the same issue - your ad will be much more effective if its the only one of its kind in that particular issue.

6. Small ezines vs. Big ezines: bigger is not always better. The big ezines with 1000's of subscribers tend to have more ads than the small ezines. A

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

lso, small ezines with only a few hundred subscribers often have a much more targeted audience than the big ezines.

7. Repeat your ads. Research shows that off the Web, an ad has to be seen about 21 times before someone acts on it; on the Internet its about 9 times. If your budget allows,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ry and have your ad repeated at least three times in a particular ezine. Most ezines offer discount packages for bulk advertising.

8. Email address vs. URL. Opinions are divided on this; some people prefer to give an email address, others prefer to give a URL. The advantage of giving an em

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ail address is that it gives you the opportunity to send a powerful sales letter to the person who responded to your ad. Its also much easier to track your ads with an email address than a URL.

9. Offer something free in your ad copy. It'll often tip the balance between a response and no re

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ponse.

10. Keep your ads short, even if you're not using the number of words you're allowed. Short ads are more likely to be read. Keep your sentences short too; they pack much more power. Use the word 'You'. Don't describe your product but tell the reader what your product can do for them

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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