Advice You - Internet and Businesses Online

Sometime in the fall of 2005, a British lad by the name of Alex Tew sailed into a perfect storm. As the web world watched, his "Million Dollar Home Page" quickly lived up to its audacious title and le

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ft its mark on internet history. Armed with uncanny marketing instincts and a good dose of luck, Alex took his novel idea, added a personal back-story, and sold a million dollar’s worth of advertising

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

in a matter of months.

Understandably, countless copy cats have gone online, but success has proven difficult to duplicate. A quick survey of these so-called “pixel-ad” brings up a large number of woe

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ully blank screens. The uniqueness of Tew's website was what drew the crowds and justified the value of his site. The second generation of pixel pages is struggling to create the same excitement.

On

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e problem is that the concept for the Million Dollar Home Page is so simple that there is little room for technical improvement. Not that people are not trying. For example, website http://www.izoomz

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

oom.com touts the ability to display a thumbnail image of the target URL as the mouse cursor rolls over a pixel ad. This feature is interesting, but it is unclear whether the thumbnail images will enco

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

rage or discourage viewers to click-through to the advertised site.

Another site with a twist is http://www.millionpixelsart.com. Instead of the standard rectangular billboard, the pixel blocks are ar

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ranged in different shapes (including a beer mug and dice). Again, the idea is interesting, but the lack of sold blocks should serve as a warning to others that success will require true ingenuity.

O

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ne of the more successful pixel-ad sites can be found at http://www.pixmeup.com. This website takes a multi-level marketing approach to pixel selling, innovating the business model rather than the for

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

at. PixMeUp currently features several densely populated pixel pages, proof of its ability to find customers.

Just as the general stores of the American West profited from the California Goldrush, it

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

may be the suppliers of the prospective pixel sellers that are reaping the greatest rewards. Domain registrars and domain hosts are also profiting from the uptick in websites coming on line. Tool de

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

velopers are cropping up left and right, offering would-be millionaires the picks and shovels needed to stake their claims. Other sites exist for the purpose of providing news and links related to the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ixel-ad phenomenon.

The pixel-ad market appears to be saturating, as evidenced by the going rate for these tiny squares of advertisement. How far has the market fallen? I found one answer on a humoro

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

us site http://www.ihatethemilliondollarhomepage.com. Its author nicely captures the jealousy and dejection felt by entrepreneurs who have failed to come close to the success of the MillionDollarHomePa

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ge. And, to spite Alex Tew, these pixels are being given away free of charge!

In time, the pixel-ad concept will continue to evolve. A mere months after Alex Tew's financial trajectory shot through

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

he stratosphere, creative descendents of the original concept are already heading off in new directions. Affiliation pixel-ad sites, such as http://www.christianmilliondollarhomepage.com/, cater to sp

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ecific causes or audiences. The pixel-selling concept takes a creative turn at http://www.WorldWideArtStudio.com, where artists can participate in the creation of art by buying the right to control por

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tions of a "digital canvas." Furthermore, WorldWideArtStudio.com turns its back on the marketing roots of pixel selling by prohibiting the display of advertisements in its artwork.

With recent Interne

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

news coverage centering on large companies like Google and AOL, I had forgotten how easy it can be for the individual to leverage the power of this global communications network. Thank you, Alex Tew,

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

for rekindling the flame of youthful innovation that was once the dominant force on the web. I confess I’ve got one or two million-dollar ideas bumping around my brain at this very moment…how about you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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