Advice You - Internet and Businesses Online

Some points to note before starting
1. Budget : How much you are willing to spend on submissions?
2. Purpose : Just increase to Page Rank or to drive traffic to your site

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

or both? Or is it for prestige and brand awareness? Most directories wont give you decent traffic, even big and popular directories Yahoo! or Business.com or Microsoft bCentral Small Bus

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

iness Directory may not increase your sites traffic.
3. Planning : The most important part of your link building campaign. You need to spend a lot of time knowing which paid director

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y to submit to and how to submit your site to, what anchor text and meta tags and keywords to use and the niche or market you are looking for.

Some general points to note when submitt

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ng to directories
1. Make sure you read the Terms of Service (TOS).
2. Always submit to the correct category (if not possible, something similar)
3. Make sure your desc

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ription is correct without any spelling mistakes
4. I would not encourage reciprocal links (or 2 way links) at all. Too troublesome and may work against you if the directory is sandb

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

oxed by Google. If you must, try linking to big directories or reputable ones.
5. Vary your descirption you submit to directories a bit so that it will look natural to visitors and S

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

arch Engines. And remember to add some keywords into your description.
6. Choose a local or a regional directory if possible, as these will at least give you a better amount of traff

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ic as well as PR.
7. Niche directories are better : They are targeted and usually have less links listed just like a local or regional directory.

Free Directory Why not? Its

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

free so just submit to them even if they are PR0. Every bit helps and you will not know whether in the future their PR will rise and can help your improve your PR as well. Just try to av

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

id link farms (directory with tons and tons of links per page) as they are useless and seldom get indexed by Search Engines at all. Also ensure that they have static text links because so

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

me dynamic links(especially those which looks like session ids) or "weird" links won't push PR to their listed sites.

Paid Directory Depending on how much you are willing to spen

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

d, you can even have links to your site from PR9 directories. My suggestion in choosing which directory is as below:
1. PR Value : Check the PR of the directory and the category in w

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

hich you want to submit your site to using Google's toolbar.
2. Static Links : Make sure they provide static links, which can help you in improving your sites PR better. Do a search

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

n Google (site:www.directory.com) and see whether their category pages and listings are indexed.
3. Number of links per page : The less the merrier. In my opinion, the optimal is 10

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

links per page. Sometimes smaller directories (and thus less links) with a decent PR can help more than a big directory (and thus tons of links) with a high PR.
4. Featured or sponso

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

red links : Its good to be on top, because Search Engine spiders will crawl from the top to the bottom.
5. Correct category : Make sure you are submiting to the correct category. An

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

make sure the category you have chosen isn't crowded or populated with too many links or it will be less effective. If your first choice category is too popular, try some other category

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

that is similar and has less links on it.
6. Do a backlink search for the directory you want to submit to. For Google, try (link:www.directory.com) and see the number of links they h

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ave. From the results, you can see the number of links to that directory and it will give you a rough indication of how well this directory is doing and whether they can maintain their PR

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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