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Not to long ago I finally decided to check out what all those little orange buttons that said “RSS” or “XML” were about. It seemed to me that either my vision was permanently impaired or eve

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ry web-site I visited suddenly spouted an RSS tag, and that proudly. I wanted to know just what those ubiquitous orange buttons meant and how they operated.

Well, in a few days I was an RSS

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

freak. Obsessed. Totally grounded in RSS mania and those little news items coming across my reader. Of course, I had a reader for my desktop, and a reader that conveniently placed itself wit

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hin my Firefox Browser. I was RSS ready for anything! And you know what. BEST OF ALL its almost ALL FREE. (If it isn’t it does not find a place on my computer!)

For those among the plebeian

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

of the world who are not familiar with RSS and what you can do with it, this article will attempt to explain the basics in RSS terminology and how you can become as obsessed with RSS as I a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

. In a future article I will attempt to explain how to create your own RSS feed as well.

RSS Feed – The information that a web site will place within the RSS file for you to read is

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

known as a “feed”. RSS Reader – The software you use, either browser based or desktop based that you use to pick up the feed and read it.

1. RSS stands for “Really Simple Syndica

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ion” or so they tell us. Well so we don’t get too complicated, RSS has gone through a few permutations based upon its versions and maturing.

Rich Site Summary (RSS 0.91)

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

RDF Site Summary (RSS 0.9 and 1.0)

Really Simple Syndication (RSS 2.0.0)

Most RSS feeds today are of the 2.0 permutation. And actually all RSS and its permutations

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

are based upon “push technology” which began to be seriously developed a few years ago.

2. RSS is based on XML (Extensible Markup Language) which is actually become incredibl

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

popular in the development of web pages and the like. (For now we will not enter too many technicalities in programming)

3. PodCasting – is a derivation of RSS where audio is pushed

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to the computer instead of just text.

4. VodCasting - is a derivation of RSS where video is pushed to the computer instead of just text.

5. There are also PictureCasting, screenc

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

asting... and I guess you are getting the picture.

6. Atom Feeds – This basically is a new syndication to replace RSS format. Whether or not it will work is up to the developers

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nd users.

7. Blogs, (a term which originally came from “weblog”) which has been all the rage in the internet lately, make extensive use of RSS feeds, pushing the information containe

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

in the millions of weblogs out to users.

So what is so great about RSS? It simply is a way of those who have content, say a newspaper, where news changes and is updated on an hourly or dai

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ly basis, to push this news to users all over the world without them logging into the web site. The user has an “RSS Reader” (many different types are available – future article) and this ne

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

s is updated automatically in the Reader on a schedule the user chooses. Thus one can be working without the need to constantly check a news web site, and still keep abrest of any news that

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s happening “out in the big world”.

Readers can handle many RSS feeds together, and it takes just a glance over to determine if something you are interested in comes through.

Why do web si

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tes and companies do this? Because it creates customer loyalty. It is another avenue of being constantly connected with the customers and viewers of their web sites. It is a way to keep the

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

eople coming back and back again.

In the next article of this series I will discuss the method by which a feed is created and then pushed out to the Net world at large for others to read it

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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