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There has been another page rank update in the last couple of weeks but it seems as though this has only affected sites which pr

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

eviously had a page rank of zero. The question many people are asking is when will google update the page rank of all of the oth

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

er sites which already showed a page rank?

This latest update seems to be very similar to the previous page rank update in whic

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

h the older sites were also not updated. When reading on various websites about other webmasters opinions on this current trend,

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

I have found a number of reasons as to why this may be happening.

Over the last couple of years there have been quite a large

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

number of link exchange programs which have been created. This have proven to be quite popular but are frowned upon by google as

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

the people who enter these programs are in a way cheating to get to the top. Most people are aware of the importance of backwar

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

links and these link exchange programs make it very easy to obtain them. In clearly states however in the google guidelines tha

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t webmasters should not take part in these link exchange programs. Webmasters who still go ahead are at risk at having their sit

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e or sites banned.

The problem could be that it is very hard for search engines like google to establish which links that each

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

site obtains are from these link exchanges and which links are actual real and valid links. It is possible that google is close

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

to finding a formula to this problem and is delaying any page rank updates on older sites until all of the finishing touches are

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

completed. My advice would be to never take part in any of these link exchange programs and that if you are currently in one, t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

o come out of it as soon as possible.

There are many valid ways of promoting a website such as via writing articles and by havi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

g good content which will encourage other webmasters to want to link to your site.

I have to say that for somebody like myself

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

who works very hard to promote my own websites, that it is quite frustrating to not be able to see the changes in the page rank,

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

as when I see my sites go up in page rank it gives me a little boost and shows me that I am still doing the right things. In a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

way it should not really matter however as I am able to see my websites have higher rankings in the search engines, this itself

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

of course is the most important thing. It is also a good thing that google are trying to stop the people who are trying to cheat

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

their way to the top, that is of course if this is the real reason why there has not been a full page rank update for some time

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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