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Every webmaster wants links (possibly a lot of them!). That's not surprisingly because links from other sites are not only a source of traffic, but

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

also a very important factor that helps a site to rank well in search engines results.

Apparently submitting your site to web directories is one

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

of the quickest ways to get links, but getting listed is sometimes much more difficult than it may seem.

The problem is that web directories are s

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

wamped by a large number of low quality submissions: poorly designed web sites, web sites without any original content or created only to display a

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

dvertisements and so on.

For this reason directory editors review hundreds of sites per day and accept only those complying to a very strict set o

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

f guidelines. There are days, and I talk by personal experience, when more than 90% of submissions are rejected, in many case without even the need

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to visit the site simply because of a poorly written submission.

If you want to increase your chances to see your site listed, it's essential to

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

understand what informations you are required to provide about your site and how to properly submit them.

At least title, description and url are

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

required by all directories.

Web site title

Directories have more or less restrictive rules about what you can or cannot have as your site

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

title. Some allow only your official domain name or company name, other are more liberal.

In any case a good title should never exceed 4-5 words

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

Using a long list of keywords as title (keyword stuffing), excessive repetitions and inappropriate punctuation must be absolutely avoided.

Web

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

site description

Many sites are rejected due to an inappropriate description. A description is not an advertisement and should never contain

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

superlatives or excessive marketing hype.

Directory listings are usually searchable by words contained both in title and description so the keywor

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ds commonly used to find your site should be included in your site description. However always write 2-3 complete sentences that sound natural do n

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ot make your description a long list of keywords.

Web site URL

You would say that people should at least be able to correctly submit their

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

own web site url. If you work as directory editor for a while you will change your mind! It happens quite frequently that a site is rejected simpl

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

y because of a mistyped url.

Never type your site url directly into the submission form. Test it in your browser, save it in a text file and copy

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

and paste from there.

Each directory can have some other specific rules, so be sure to carefully read the submission guidelines and comply to any

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

special requirement.

It's said that you never get a second chance to make a good first impression: directory editors read the informations you sub

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

mit before visiting your web site. Learn to properly write your submissions and you will greatly increase the chances to have your website accepted

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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How many of your customers are loyal customers? More importantly do you know why they are loyal customers?

I would imagine that I am not the only webmaster in the world who is trying to increase the page rank of their website. I have heard a number of comments recently where people in various forums have said things such as, page rank is dead and that it does not really matter what the page rank of your site is. This may well be correct, however I still believe in the basic principle of the higher your page rank is, the more traffic you are likely to gain. Nobody will ever be able to convince me that a site with a page rank of four gains more traffic than a site with a page rank of eight. In this article I am going to write about how webmasters can gain this higher page rank, advice which I use everyday myself and advice which has stood me in very good stead thus far. I just hope that Google do not suddenly decide to change the rules as it would mean that I would have to learn all over again.

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