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Of course, you have to isolate each individual ezine traffic source for th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

is to be effective. Why not just advertise in one ezine at a time? In th

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

at case, you would eventually determine which are better than others, but

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

at the cost of time. By advertising in multiple ezines at one time, you c

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

an get faster results, so you can begin to regularly advertise in the ezin

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e(s) that produces the best results.

Probably more important than that is

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

for you to be able to immediately see the difference between each ezine s

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ource. For example, if you only advertise in one at a time, your first tw

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

o ads might be extremely effective, and you will gain a false sense of con

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

fidence in the effectiveness of ezine ads. On the other hand, your first

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

few ezine ads could be complete losses, and you would then get a false sen

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

se of aversion to ezine advertising.

The bottom line is, if you select a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

budget, and then spread out several ezine ads, then you can get a realisti

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

c picture of what ezine advertising can and cannot do for you.

So how do

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

you actually do the advertising?

With most ezines, you are going to have

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

several choices of ads. You can run classified ads in the ezine, which is

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

generally a 3-5 line ad, in a list of other ads from other people. You c

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

an purchase a ‘sponsor’ or ‘position’ ad, which generally gives you a spec

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ified number of lines on a specific portion of the email itself. You can

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

also purchase ‘solo’ ads – which are generally your ad alone in the email.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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