Advice You - Internet and Businesses Online

Would you like to bring your far-flung family and friends together with a members-only web site for sharing travel photos and family news?

Web sites with restricted access are called membership sites. It used to be the case that they wer

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e developed only by experienced web developers who were experts in database security and dynamic web pages. Microsoft has opened up new avenues for novice and hobbyist developers by providing a free development environment and Personal St

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

arter Kit designed to get family web sites up and running.

The Development Environment
Go back a few years and the preferred development environment for membership sites was MySQL for the database and PHP for the programming

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

The PHP/MySQL route is still an excellent option but one that comes with a steep learning curve.

With the launch of Visual Web Developer Express (downloadable from the Microsoft website), Microsoft has provided a free development enviro

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nment aimed at novice developers. You want a registration and login page on your web site? VWD Express comes with ready-to-use membership features that let the developer "drag-and-drop" login controls onto their web pages.

Of course, the

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

Microsoft option requires a Windows operating system and web server. This won't wash with Linux devotees, but is appealing for developers used to working within a Windows environment.

The Personal Starter Kit
Even with a grap

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

hic drag-and-drop development environment, there is quite a bit of coding required for a full-blown membership site. Creating sites from scratch is challenging even for experienced developers. It's easier to work with an existing applica

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ion that provides most of the functionality required.

The Personal Starter Kit is a Microsoft-provided sample application designed for family web sites. Its membership features allow for secure login to share photos and family news. This

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

kit actually comes with VWD Express - you will see it as an option when you use the tool to create a web site. You then use VWD Express to modify the sample application with your own personality.

The Database
When you start

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

using membership features in your VWD Express web applications, a standard security database is created on your development PC for the storage of data such as login details. VWD Express uses SQL Server Express as its database engine, whic

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

h is a scaled down version of the Microsoft flagship SQL Server database.

For those who are new to databases, Microsoft seeks to insulate you as much as possible from complex database tasks. VWD Express provides a visual environment for

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

working with web components that access data.

Potential Pitfalls
It's possible for a novice developer to get the Personal Starter Kit up and running on a PC in a single evening, followed by an enjoyable weekend of adding pers

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nality to the look-and-feel of the site. The potential pitfalls usually occur when trying to put the web site live. I'll share with you my best advice for a smooth deployment.

1. Go live early and often!
It's much easier to get a sm

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

all website live and working than debugging pages and pages of modifications and extensions. I advise getting the Personal Starter Kit working on your live host site with minimal changes. A successful deployment can be followed by increme

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tal and ongoing modification.

2. Modify the database connection
Judging by internet forums, getting the live web pages to connect to the live database is the most common problem experienced. Because VWD Express takes care of setting

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

up the database connections in the local configuration file, developers get stuck on modifying the details for a live configuration. Take heart – once you have this issue sorted, you won't have to look at it again.

3. Work with your liv

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

database security restrictions
Many hosting providers do not let you run remote tools against the live database. Although VWD Express comes with an application for managing web site members, you won't be able to use it on the live d

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

atabase in this case. There are a number of alternative options depending on your database expertise. Novice developers may want to use a packag

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d set of database programs, known as stored procedures, to manage users.

4. Understand the Live Database
Many hosting providers do not support SQL Server Express. Instead, you will have to get your application working with SQL S

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

erver itself (its big brother). Don't worry – installing the database structures is done via scripts, and your hosting provider should have more information. Be prepared to spend a bit of time getting to know the live database environment

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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