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Advice You - Web 2.0 Provides A Wonderful Trip Down Memory Lane
In the last couple of years, web professionals have been gushing about Web 2.0. A look at Wikipedia tells us that the term Web 2.0 was developed by O'Reilly Media that refers to a second generation of web services that emphasize online collaboration and sharing among users. Go beyond
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
Wikipedia and look at other sources and you will very likely get about a thousand and one descriptions of Web 2.0. So it appears that Web 2.0 is a different thing for different people although social networking seems to be a common denominator among all the different descriptions. T
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
ke note though of the terms "online collaboration" and "sharing among users" because they will figure prominently in what we are about relate.
Now before anything else, this article is neither an endorsement nor criticism of Web 2.0. But to an old-timer such as myself, Web 2.0 is a
Now before anything else, this article is neither an endorsement nor criticism of Web 2.0. But to an old-timer such as myself, Web 2.0 is a
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
ehash of some of the online things we used to do back in the late 80's and early 90's. For those of us who have been doing the rounds of the internet even before Netscape was born, we had our own social networking scene then. They were known as Bulletin Board Systems or BBS's. In tod
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
y's web world, bbs is synonymous with online forum--the sites which commonly have people contributing answers to questions posted by fellow users.
Back in the early days, bbs's were literally a system in themselves. To be able to access a bbs in your area, you need a modem hooked up
Back in the early days, bbs's were literally a system in themselves. To be able to access a bbs in your area, you need a modem hooked up
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
to your computer. These modems would use the regular telephone line to achieve connection. As the person trying to access, also known as the client, you would also need a "terminal" application to issue the dialing instruction. Two of the most common terminal programs were Telix and
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
Hyperterminal, and oh, we were mostly using either DOS or Windows 3.1 then, and a few using either Linux or OS/2. Oh my God, OS/2!
If you are now trying to catch your breath from the description of the processes involved just to access a bbs back then, it was indeed cumbersome to a
If you are now trying to catch your breath from the description of the processes involved just to access a bbs back then, it was indeed cumbersome to a
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ertain extent. Too many application requirements to make a simple connection. But to fast-forward a bit, once you get connected to a bbs, there were also a thousand and one things you could do while online, most if not all of which were equally as exciting as what some of today's won
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
erful web applications have to offer.
Online collaboration and sharing were two of the biggest attractions of the bbs community especially if you were a member of a bbs network. The biggest bbs network at the time was known as Fidonet and amazingly, their website still exists today-
Online collaboration and sharing were two of the biggest attractions of the bbs community especially if you were a member of a bbs network. The biggest bbs network at the time was known as Fidonet and amazingly, their website still exists today-
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
www.fidonet.org. The online collaboration and social networking aspect came in the form of the "message bases". Once logged on to a bbs, you could read and write messages in the hundreds of message bases which were then circulated among the thousands of bbs's around the world that we
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
e members of Fidonet. The message bases each had a specific topic ranging from social to entertainment to educational to technical to religious and on and on.
The sharing part came in the form of the "file bases". In fact, I dare say that the golden era of shareware programs came
The sharing part came in the form of the "file bases". In fact, I dare say that the golden era of shareware programs came
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
at the same point when bbs's were at their height in popularity. The file bases were the areas where a bbs user could download many different softwares on a try before you buy basis, hence the term "shareware". A interesting sidelight to file downloading then was that computer viruse
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
were just starting to proliferate and there were not that many antivirus solutions available. I suppose we all just had to grin and bear, and kept our fingers tightly crossed.
Another attraction of the bbs's were the availability of online games. The games were nothing like today's
Another attraction of the bbs's were the availability of online games. The games were nothing like today's
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
which are almost realistic in their graphics and surround sound. The bbs games then were mostly text-based, but equally colorful and adventuresome. Like the message and file bases, the games that had tournaments in them were circulated around the world so you could be sitting in fron
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
of your computer in a remote island in the Pacific playing against someone living in the heart of London.
The drawback to accessing bbs's was the busy line. Most bbs's ran on only one phone line and if a user was hogging his/her online time, other users were denied access. We also
The drawback to accessing bbs's was the busy line. Most bbs's ran on only one phone line and if a user was hogging his/her online time, other users were denied access. We also
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
entioned above that connecting to a bbs could be cumbersome chore given a lot of requirements involved so the whole process was not too appealing to those who were not predisposed to going through the steps.
Remember too that internet access was not in the mainstream at the time so
Remember too that internet access was not in the mainstream at the time so
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
the exchange of messages, files and games were not done in real-time. Transporting the messages, files and games around the world was expensive. The highest modem speed that could have been achieved then was 28.8 Kbps so the more the messages and files and games, the longer time you
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
ad to spend connected to the internet provider. In short, it was quite expensive for the operator of bbs to maintain their systems and for the user, the experience could been frustrating especially when having to deal with busy phone lines. And yes, bbs's were mostly free for anyone
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
o access. When the internet started to become mainstream, bbs's started to fade away.
So the next time you read something hyping the virtues of Web 2.0, there is no need to get too carried away. The trail had been blazed, albeit in a manner not as sophisticated as today's web is cap
So the next time you read something hyping the virtues of Web 2.0, there is no need to get too carried away. The trail had been blazed, albeit in a manner not as sophisticated as today's web is cap
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
ble of. Indeed the ability to collaborate in almost real-time and the eye-catching presentations Web 2.0 can deliver could not have been achieved back then, but the elements are essentially the same. If not for anything else, Web 2.0 has provided a nice little stroll down memory lane
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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