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    The organization has to acquire the rights to post any copy right preserved information on its web site. All terms and conditions of usage must be included at the notices and disclaimer page. Web hosting agreements are also nece
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    ssary when it comes to proper management of the web site.

    The organization has to set the policies and rules for the internal use of the web site. Employee's internal use can often be harmful for the organization, as the confident
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    al information can be revealed and the improper functioning of the web site can take place. The jurisdictional issues have to be solved in accordance with the laws of the target market unit. The taxation process depends on the jur
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    isdiction of the purchaser and on the web operator location.

    There are many regulatory issues that web sites face. The US sites are mostly self regulated. European based operators are mostly government regulated. Individuals and l
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    rge organizations try to minimize and avoid the government's interference. The fraud and internet terrorism problems are not being given as much attention as needed. In regards to security matter US laws are traditional.

    Every or
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    anization has to follow certain set of business ethics rules. Web sites come across a number of ethical issues as well. Most important the web site, global in particular, has to post only the relevant and trustful information. It
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    is essential to make sure that the organization has the rights to use the information it posts; all the copy rights have to be preserved. The ethical issues very from company to company. Many organizations establish the code of eth
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    cs. The set of guidelines to follow appears to be helpful when it comes to company's ethical behavior and success.

    Each one of the three web sites (travelocity.com, cheaptickets.com and priceline.com) has the privacy policy which
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    iscusses in details the organization's use of the customers personal information. The privacy policy plays a great role in the establishment of the trustful, long lasting and secure customer-organization relationship. The terms a
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    nd conditions pages are also necessary. They are developed and posted on the given web sites.

    Travelocity protects its customer's personal information using the 128-bit SSL (Secure Socket Layer) encryption, which is the highest in
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    industry standard. To further ensure the safety of the personal information, the travelocity.com off-line database is located in the Sabre, Inc. secure underground data center. Travelocity provides the links to its international si
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    es and partners. Every customer outside the US by simply clicking on the link will be transfered to its home country travelocity web page.

    Cheaptickets doesnt specify the programs they use to secure the personal information. Unlik
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    e the travelocity, there is no mention of the security top priority. Chepatickets assumes no liability for the loss of any information transmitted via the World Wide Web. All the personal information is forwarded to providers and i
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    secured by them. However, there is no mention of how the information is secured by providers and where exactly it is kept. International issues are not being discussed on the web site. There are no links or references for the non
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    S resident customers to use.

    Priceline appears to be the most secure web site of all three. Its privacy policy states that the information collected is stored in a single, secure database, accessible only by priceline. It is also
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    guaranteed that the company employs reasonable and current Internet security methods and technologies.

    Priceline has created a secure environment for credit card transactions. The web site uses Secure Socket Layer technology to
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    ncrypt all personal information including credit card number, name and address to prevent customer’s information from being read during transmission over the Internet.

    There is a number of links for the international customers to
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    se. They will be immediately transfered to the priceline international web pages.

    Priceline has branches in Great Britain, Taiwan, Hong Kong and United States. Priceline website is operated by Hutchison-Priceline (Travel) Ltd, an
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    independent company formed with investments from Hutchison Whampoa Ltd, a Hong Kong-based multinational conglomerate with operations in 36 countries, and priceline.com Inc., based in the U.S.

    Priceline is considered the best trave
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    deal provider on the internet. The reason for company's success is its ability to identify customer's concerns and possible issues. And most important is priceline’s ability to avoid the possible problems prior to their occurrence


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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