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  • Advice You - It's Always the Poor that End Up Paying for Everyone Else

    “She was poor but she was honest,
    Victim of the Squire’s game,
    First he loved her then he left her,
    Ain’t it all a bleedin’ shame?”

    Just like the anonymous poor girl in the above Victorian Music Hall song, it’s those who can afford it the least that usuall
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    y end up paying the most.

    They say money is the root of all evil. Well I am not too sure about that but money (or the lack of) certainly does do strange things to people.

    Everybody dreams of winning the Lottery and being able to walk into your job the next day and polit
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ly (or not, depending on your relationship with your employers) being able to tell your employer what to do with it. It seems that with either too much or too little, the end effect is the same and that is, of course, trouble.

    You could recant an almost endless list of p
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    latitudes about money and the common thread would be the pursuit (and absence) of happiness.

    In this article my main concern is the over arching effect that the lack of money has on most people. Now the obvious initial reaction would be that it is fairly obvious what a l
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ck of money does. It restricts what you do at the weekend, how much money you have to spend on clothes, eating out etc or does it?

    It seems that we are a generation that is being consumed by debt and by and large we don’t seem to appear to be troubled too much by it. The
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    downside of all of this is that in the United Kingdom we see the Government release an ever increasing quarterly number in the applications to submit to the Bankruptcy Court and in the United States we see a government that is presiding over a National Debt that is the la
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    rgest ever seen since records began.

    With such apparent Public indifference to the side effects of borrowing to excess; is it any worry that this seems to be increasing rather than decreasing? Yet if we are not careful, we are sitting on a financial time bomb that is pro
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    rammed to explode in our faces in the not too distant future.

    You see being consumed by debt does strange things to people. They say that if you owe the bank ?30,000 and they press you to repay, it is your problem, but, that if you owe the bank (or a collection of banks)
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ?300.000 it is their problem. This is by and large down to what degree of “Russian roulette” (as they call it in financial circles) you choose to play with.

    The newspaper columns are regularly filled with stories of over stressed individuals who have borrowed too much o
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    their credit cards, can’t repay and have then gone and committed suicide purely as an adverse reaction to the intolerable stress levels that they have apparently found themselves in. Yet at the same time you see a daily procession of individuals cheerfully emerging from
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    he Bankruptcy Courts having declared themselves bankrupt or a degree of bankruptcy that has enabled them to head straight away to the nearest restaurant to celebrate!

    Most Financial Institutions when pressed with the unenviable role of calling in debts react in a similar
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    fashion and that is to start to pile on a list of never ending bank charges or financial fees to raise the eventual amount of debt to almost unrecognisable levels. It is understandable that to the average man in the street that when faced with an ever increasing and neve
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ending mountain of debt that the unthinkable in terms of suicide becomes more appealing. After all quite often when the answer to an initial plea of “I can’t afford to repay” is replied to in terms “never mind, have some more and we will change the interest rate, make it
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    slightly cheaper but extend the term” thereby potentially making it doubly expensive but the poor recipient of this largesse is so relieved and grateful that they fail to check this fact in the small print.

    Quite frankly, the Banks get what they deserve in the end of th
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    day and all of this hand wringing routine of “we will have to pass these costs onto our other customers thereby making their accounts more expensive” is complete hogwash. The Banks are experts in shovelling money round the system and you can bet your bottom dollar that t
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    eir eyes light up with glee when they close the front door and open the back door and via a discrete (and sometimes not so discrete) third party decide to play “fast and loose” in the euphemistically described “sub prime” sector. Here they revel in the fact that they can
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    by and large charge whatever they like in rates and damn all others because they know that the poor and unsuspecting borrowers have nowhere else to go.

    I once had lunch with a Financial Advisor who gleefully admitted that it was “Sub-prime” lending he was looking to deve
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    op and that he could close these sorts of deals all day, every day. He was not one tiny bit interested in the conventional market of standardised borrowing. “No way,” He declared, “it’s only when people get themselves into trouble can we start to make some real money”.

    I
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    t is one of the greatest paradoxes of modern day society that it is more expensive for those who cannot afford it in the first place to borrow than it is for those who can. The trouble is that the Banks know it; they know who need the money most and they also know how to
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ake the most profit in between.

    However this kind of reckless money lending and loan sharking cannot go on for ever. The day will come when if they are not too careful, the mountain of debt will become just a little too large to be dealt with by moving it around slightly


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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