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One of the huge advantages of credit cards, and one of the many reasons they continue to grow in popularity, is the easy

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

access they offer when travelling abroad. Not only can they be used with ease to book hotels or pay for car rentals, but

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

they can also be used at cash machines around the world for instant and safe access to local currencies. They are also fa

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r safer than carrying cash, which can be stolen no matter where in the world you are travelling, and more convenient than

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

travellers cheques which can often be difficult or time consuming to cash.

However, with this added convenience comes e

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

xtra costs. When you use your credit card to make purchases in foreign countries you will be charged currency conversion

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

fees and sometimes also, a loading fee by your credit card provider. This means that there can be two sets of charges add

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d to every purchase you make while abroad. It can be frustrating to get home and find that along with each transaction th

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ere is a conversion fee of a couple of pounds and another loading fee also of a few pounds. While it is possible to get c

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ards that have lower fees for foreign currency transactions, it is difficult to avoid these charges completely. Most peop

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

le put up with them because of the sheer convenience of using the card but there are ways to avoid them.

One way is to t

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ake out cash from a cash machine with your credit card. The main disadvantage of this is that you will be charged interes

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

t on cash advances immediately, and are not allowed the usual interest free period which lasts until your next bill. Howe

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ver, if your alternative is to make lots of small purchases, with each one incurring its own separate charges, you may be

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

better off taking this once off fee, then lots of smaller ones.

If you are organised enough, you can pay extra money ont

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

o your credit card before you leave, so that you will in effect have paid off the cash advance before you take it out, an

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d thus avoid paying interest on it. Another option, if you have money in your bank account and an internationally recogni

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

sed debit card, such as maestro, is to take out cash on your debit card. While this will incur some foreign charges, at l

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

east you will not have to pay any interest on the cash.

At the end of the day, for many people, being able to rely on us

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ing their credit cards abroad is a god send and the fees are a reasonable price for the convenience and security afforded

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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