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As one of the many AAdvantage cards by Citibank, the Citi Platinum Select®/AAdvantage World Mast

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

erCard caters to individuals with a good credit score and who frequently travel on American Airl

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ines.

The Citi AAdvantage World MasterCard awards cardholders with one AAdvantage mile for ever

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y dollar spent on the card. Accumulated miles can then be redeemed for hotel stays, car rentals

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nd free travel via American Airlines, American Eagle, American Connection and other participatin

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

g carriers, with no blackout dates. There is a maximum cap of 100,000 miles that can be earned p

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

er card each year, which is well within reason. This limit does not apply for the other AAdvanta

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ge cards from Citibank. However, the miles will expire if there is no account activity for three

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

years.

The difference between this AAdvantage card and others is not very apparent. Aside from

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

the maximum cap, the Platinum Select card offers 15,000 Bonus Miles on the first purchase as wel

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

l as no ‘pre-set spending limits’, which provides cardholders with room to go over their credit

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

limit once in a blue moon. Also, as this is a Platinum Select card and not a full fledged Platin

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

m card, this card with several benefits that are typical of a Platinum card such as $1,000,000 i

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

n travel accident insurance for airline tickets purchased with the card.

Also, the card’s APR i

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s somewhat above average as compared to other cards of the same category. On the flip side, ther

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e is an $85 annual fee attached, thus making this card rather costly to own and use. To add to t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e cost, a minimum rate of 19.99% is imposed for cash advances, regardless of any drop in the Pri

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

me Rate with which the APR is dependent on.

To sum it up, individuals traveling frequently with

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

American Airlines and partnering carriers will reap the full benefits from owning the Citi AAdv

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

antage World MasterCard, as most of these benefits are specially tailored for this target market

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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